2024 asa guidance glp-1 receptor agonists perioperative How should we approach patients on agonists? Check out this excellent editorial from Dr. Girish Joshi, "Clarifying the Guidelines and Decoding the Enigma: Strategies for Anesthetic Management of Patients on Glucagon-Like ASA Guidance on GLP-1 Preoperative

Evidence is emerging that glucagon-like peptide-1 (GLP-1) receptor agonists have anti-inflammatory and chondroprotective properties independent of their effects on weight loss

Daily GLP-1 support supplement formulated to complement weight loss medications

Some studies report solid food remnants in the stomach even after prolonged fasting

Together, this combination does not provide clinical benefit due to similar mechanisms of action (see picture below)

Here, the authors review the physiological roles of GLP-1, the potential renoprotective mechanisms of incretin-based therapies and the available renal outcome data from clinical trials.

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