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Doctors operate under the assumption that all patients convert T4 to T3 at an equal rate which means that they dont feel this conversion process should be taken into account

Baseline blood work before starting Before your first dose of any GLP-1 medication, get baseline blood work that includes a complete blood count, comprehensive metabolic panel, ferritin, serum iron, total iron binding capacity, zinc, vitamin D (25-OH), B12, folate, TSH, free T3, free T4, and hemoglobin A1c

This premise is reinforced by the discovery that different immune cells, including B and T lymphocytes, as well as myeloid-lineage cells such as monocytes, eosinophils, and neutrophils, express GLP-1Rs ( 3.1 Innate and adaptive immune response In rat models of systemic inflammation, a GLP-1 RA, exendin, significantly lowered pro-inflammatory cytokine levels, including IL-1, IL-6, TNF-, and interferon-gamma (IFN-) ( in vitro studies, GLP-1 RAs have demonstrated the capacity of promoting an anti-inflammatory state by influencing immune cell differentiation

Some specific considerations apply to certain GLP-1 medications

Your weight-health hormones not your willpower, macros, or even medications regulate the systems that determine whether you age well

doi: 10.1016/S2213-8587(20)30075-9 54 HusainMBirkenfeldALDonsmarkMDunganKEliaschewitzFGFrancoDRet al