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Separate research published in The British Journal of Nutrition found that when adults at risk of diabetes began regularly consuming more wheat fiber, the bacteria in their guts gradually adapted to the extra fiber and their bodies began making more natural GLP-1

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However, retatrutide is not yet approved for any indication as of 2026, and its eventual FDA labeling may specify obesity treatment only, with glycemic benefits listed as secondary endpoints rather than primary indications

BioMed Pharmacother

Unfortunately, high costs and insurance barriers have led to 40% of GLP-1 prescriptions going unfilled , with uninsured patients and non-Hispanic Black and Hispanic patients disproportionately affected

N., Wharton, S., Connery, L., Alves, B., et al