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Lancet Diabetes Endocrinol, 10 , 193206

GLP-1RAs aid in weight loss by regulating the gut-brain axis and interacting with leptin, while weight loss can alleviate the harmful effects of obesity on the body, particularly in knee OA, by reducing joint loading and inflammation
A large study that compared tirzepatide to semaglutide showed that in non-diabetic, overweight adults, the risk of gastroparesis was much higher in semaglutide recipients compared to tirzepatide

Here are some strategies dietitians can put into practice when counseling patients

& Abdelghany, R

When the focus shifts from temporary loss to genuine health transformationrestoring hormonal balance, improving nutrient absorption, and rebuilding metabolic strengththe body doesnt just lose weight
