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Retatrutide affects three hormones -- GLP-1 and GIP, each of which are targeted by similar weight loss drugs, and glucagon, which none of them targets -- and could be best for people looking to lose larger amounts of weight, said the company's chief scientific and product officer, Dan Skovronsky

First, the sheer amount of body weight loss: Around one-quarter total body weight loss in under a year

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The gut-brain axis and GLP-1 production GLP-1 (glucagon-like peptide-1) is produced primarily by L-cells in your small intestine and colon
doi: 10.1016/B978-0-12-800977-2.00004-8 84 GuoJ