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Unlike ER66, ER36 lacks transcriptional activation domains (AF-1 and AF-2), but retains dimerization, DNA-binding and partial ligand-binding domains 19

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Genetic Predispositions and Medication Response Variability Individual variations in GLP-1 receptor (GLP1R rs6923761) and GIP receptor (GIPR rs1800437) expression influence how efficiently each medication engages target tissues

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