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"Structural basis for GLP-1 receptor activation by LY3502970, an orally active nonpeptide agonist"

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That connection, that trust, is what turns a prescription into a transformation

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Abbreviations AE Adverse event BMI Body mass index BP Blood pressure CI Confidence interval CV Cardiovascular CVOT Cardiovascular outcome trial DBP Diastolic blood pressure ETD Estimated treatment difference GIP Glucose-dependent insulinotropic polypeptide GLP-1 RA Glucagon-like peptide-1 receptor agonist HbA1c Glycated haemoglobin A1c MACE-4 Major adverse cardiovascular events proAND Pro-atrial natriuretic peptide SBP Systolic blood pressure T2D Type 2 diabetes WL-D Weight-loss dependent WL-IND Weight-loss independent Author contributions HP contributed to the conception of the work

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That 30.3% is a two-year result in people with a BMI of 35 or higher

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Metformin is an oral prescription drug used to treat type 2 diabetes mellitus

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