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Many patients achieve excellent outcomes on semaglutide

More serious concerns are less common but important

Earlier this month, new research published in eClinicalMedicine showed that semaglutide was associated with significantly lower risk of dementia and nicotine misuse versus other diabetes therapies, such as sitagliptin and glipizide

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Since 2020, the number of prescriptions for GLP-1 drugs has more than tripled

Histone deacetylases (HDAC2), a member of the HDAC family, is correlated with insulin signaling components in postsynaptic glutamatergic neurons of the adult mouse hippocampus, and hyperactivity of the HDAC system (including HDAC2) may result in the suppression of the insulin signaling system and consequent disruption of synaptic plasticity in type 2 diabetes