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GLP-1 is an incretin hormone produced by the gut that has multiple effects on metabolism and weight regulation

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In bone, GLP-1 binding to its receptor promotes bone marrow mesenchymal stem cell osteoblast differentiation and inhibits its differentiation into fat cells, thereby promoting bone formation and improving osteoporosis [15]

[DOI] [PMC free article] [PubMed] [Google Scholar] 79.Kawai Y, Uneda K, Yamada T, Kinguchi S, Kobayashi K, Azushima K, et al

It is released primarily in response to food intake and controls the secretion of insulin in function of the glucose level

Your body is experiencing the biggest shock to its system, and you're also likely titrating your dose upwards