insulin vs glp-1 Receptor Agonists as Treatments for Type 2 Diabetes Frontiers | GLP-1R in diabetes

Animal studies indicate a potential risk of thyroid C-cell tumors, raising concerns about medullary thyroid cancer in humans, though clinical trials havent confirmed this link

Whilst many of the cells are located in the small intestine and would be expected to experience changes in the concentration of luminal nutrients, such as amino acids released from protein digestion, a significant proportion of the cells are located more distally in the colon and rectum where they are less likely to experience changing nutrient levels directly

GLP-1 agonists like semaglutide have been proven to be effective in helping people lose weight

the initial evaluation, lab review, dose titration, and monthly check-ins can all be done remotely

Several studies have reported that transient increases in serum glucose are associated with acute inflammatory processes and endothelial dysfunction in both diabetic and non-diabetic patients[14]

Patients should be encouraged to prioritize nutrient-dense foods and ensure adequate protein intake (typically 1.2-1.6 g/kg of ideal body weight daily during active weight loss, with higher amounts for those engaging in resistance training)