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Interestingly, glucagon-like peptide-1 receptor agonists (GLP-1RAs), used in the treatment of T2DM and obesity, are known to show pro-cognitive and neuroprotective properties, and exert modulatory effects on immune, endocrine and metabolic processes in the central nervous system

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This paper introduces an AI-driven pipeline for efficient de novo design of peptide drugs, focusing on GLP-1 receptor agonists (GLP-1RAs) with extended half-life and enhanced efficacy

This combination leverages amylin's ability to promote feelings of fullness and slow stomach emptying

The effect of GLP-1 (Green arrows) could alleviate DSS-induced (Red arrows) ulcerative colitis through reducing the secretion of inflammatory cytokines, i

Vanessa Mack (Dean)