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This review explores the complex interplay between hyperkalemia and the use of guideline-directed medical therapies (GDMT), such as reninangiotensinaldosterone system inhibitors (RAASi) and steroidal mineralocorticoid receptor antagonists (sMRAs), including spironolactone and eplerenone, which are currently recommended in guidelines for improving outcomes in heart failure with reduced ejection fraction (HFrEF)
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Danish pharma major Novo Nordisk presented a new sub-analysis from the large clinical trial STEP UP at the European Congress on Obesity (ECO) taking place in Istanbul, Turkey, showing that the higher dose of the weight loss drug Wegovy (semaglutide) Is highly effective at helping people with obesity lose significant amounts of weight regardless of how quickly their body responds to the treatment.
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