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The assessment was performed using the major adverse cardiac event (MACE)4 composite that includes cardiovascular death, myocardial infarction, stroke, and unstable angina hospitalization

A patent application becomes abandoned for failure to file a complete and proper reply as the condition of the application may require within the time period provided, or failure to pay required maintenance fees

This mathematical relationship is why the manufacturer sets both a time limit and a temperature limit for room temperature storage