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The American Diabetes Association (ADA) guidelines updated in 2023 recommend GLP-1 receptor agonists as a preferred treatment option for many patients with type 2 diabetes, particularly those with or at high risk for cardiovascular disease or kidney disease

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Retatrutide: A Promising Option for Non-Diabetic Weight Loss in Clinical Trials Key Takeaways Retatrutide, a new triple receptor agonist, appears particularly promising as a non-diabetic weight loss agent because it targets glucagon, GLP-1, and GIP

Exenatide exerts a PKA-dependent positive inotropic effect in human atrial myocardium: GLP-1R mediated effects in human myocardium