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In clinical trials, people taking Contrave lost an average of about 8% of their initial body weight after 56 weeks, compared to less than 2% in those who took a placebo (inactive medicine)

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Thats why well-known drugs like Ozempic, Wegovy, Saxenda, and Mounjaro are administered weekly or daily via injection

Effects of semaglutide and empagliflozin on oxygenation, vascular autoregulation, and central thickness of the retina in people with type 2 diabetes: A prespecified secondary analysis of a randomised clinical trial

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