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The most common side effects were stomach-related issues like nausea, vomiting, constipation, and diarrhoea

One of the most prevalent adverse effects of perimenopause and menopause, affecting at least 50% of women, is weight gain

Patients should seek medical attention for persistent upper abdominal pain, jaundice, or fever

Using data from the TriNetX US Collaborative Network, investigators identified patients with diabetes and overweight or obesity who initiated tirzepatide and compared them with a matched cohort receiving lifestyle intervention alone, without exposure to weight-loss medications

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Future Directions and Research Opportunities Triple Agonism and Beyond The success of dual agonism has stimulated interest in triple agonism approaches that add glucagon receptor activation to GIP and GLP-1 targeting