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Signs of an allergic reaction: Swelling of the face, hives, or difficulty breathing

Not Rotating Sites: This can lead to skin irritation

468 Specifically, these agents can attenuate the excitability of carotid body cells and diminish sympathetic activation, ultimately leading to a reduction in sympathetic responses

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Both states require a good-faith medical exam by a licensed provider before prescribing, and South Carolina law specifically bars prescribing based only on an internet questionnaire