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GLP-1 receptor agonists like semaglutide have shown protective effects on kidney function in multiple clinical trials, particularly for people with type 2 diabetes

US pharma giant Pfizer presented detailed results from multiple Phase IIb studies of berobenatide (PF-3944), an investigational, potential first-in-class monthly GLP-1 receptor agonist (GLP-1 RA) peptide, during a late-breaking expert symposium at the 86th Scientific Sessions of the American Diabetes Association (ADA).

Glucagon-like peptide-1 (GLP-1) drugs are very effective for weight loss and improving metabolic health, and therefore may reduce risk for breast cancer

Nevertheless, the overall drug exposure was not considered clinically significant

EGD was performed showing a large amount of food in the stomach but no gastric outlet obstruction with ability to visualize the jejunum