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Yes, weight loss plays a major role

Myocardial Inflammation Predicts Remodeling and Neuroinflammation After Myocardial Infarction

Top-dose phentermine and topiramate was not cost-effective, with an ICER of $317,010 per QALY gained vs lifestyle counselling

References Chao, A

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Herbalife's relatively stable FY2025 net sales versus Medifast's weaker revenue path suggests that companies positioned as complementary to GLP-1 use have held up better than those forced into a late pivot