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Clinical data indicated that the population receiving AMG 133 treatment exhibited a clear dose-dependent weight reduction

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Clinically relevant bradyarrhythmias were more often observed than expected ( Although some post myocardial infarction (post-MI) and dilated cardiomyopathy (DCM) patients with HFmrEF face an increased risk for arrhythmic sudden cardiac death (SCD), current guidelines do not recommend an implantable cardiac defibrillator (ICD)