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We have found a significant and clinically meaningful reduction in ICP in the treatment arm as compared to the placebo arm both acutely and after 12 weeks of dosing

Bitter foods and compounds activate GLP-1 pathways Bitter taste receptors (T2Rs) exist not just on the tongue but throughout the gastrointestinal tract, including on L cells

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Biochemistry 40 , 1318813200 (2001)

Transparency: The lead author (the manuscripts guarantor) affirms that the manuscript is an honest, accurate, and transparent account of the study being reported