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In their study, Bose et al
Further investigation is warranted to elucidate the neuroendocrine mechanisms underlying these interactions and to identify patient subgroups most likely to benefit from GLP-1based treatments

The same group also showed that giving GLP1RAs increased cAMP levels, which, in turn, activated the CREB transcription factor for increased IL-10 (an anti-inflammatory cytokine) production

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Clinical Pharmacokinetics, 60 (10), 13351348
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