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For some people, the caffeine-containing variants (used in the energy patches and present in some weight-loss formulations) can cause jitteriness, sleep disruption, or palpitations

doi: 10.3389/fmed.2022.875430 Summary Keywords glucagon-like peptide-1 receptor agonist (GLP-1RA), incretin based therapy, glucose-depent insulinotropic peptide (GIP), dual agonists, tirzepatide, type 2 diabetes Citation Gallwitz B (2022) Clinical perspectives on the use of the GIP/GLP-1 receptor agonist tirzepatide for the treatment of type-2 diabetes and obesity

This is particularly critical before surgical procedures, as tirzepatide's effect on gastric emptying may necessitate adjusting the timing of the last dose prior to anesthesia to reduce aspiration risk

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This pilot will be a huge social and healthcare experiment

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