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doi: 10.1172/jci78371

Although the mechanism of action is not fully understood, and GLP-1 and GIP receptor-related mechanisms may be involved, initial results show encouraging prospects in the treatment of obesity

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injection-site reactions occur with the weekly subcutaneous formulations

6,7 Long-term trials evaluating the effects on the immune system may be warranted owing to increased reports of nasopharyngitis, urinary tract infection, and small elevations in white blood cell count