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While further behind alcohol and nicotine research, preliminary studies are examining whether GLP-1 agonists could complement existing treatments like buprenorphine and naltrexone for opioid use disorder

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doi: 10.1016/j.clnesp.2022.01.014

Based on the proglucagon nucleotide sequence, prior assumptions regarding processing enzymes led to an erroneous GLP-1 sequence longer by 6 N-terminal amino acid residues [3]

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Although they are typically mild and transient, these AEs can affect adherence and limit dose titration