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Testosterone influences mitochondrial function directly
R.WuZ.MorisseauC.et al (2008)

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Moreover, studies have suggested that a link exists between Akkermansia muciniphila and cognitive performance, and the underlying mechanism involves decreasing the level of pro-inflammatory cytokine interleukin (IL)-6 in both peripheral blood and the hippocampus (Zhu et al., 2023)

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Maag-darmklachten, verlies van spiermassa, mogelijke (zeldzame) ernstige complicaties, en de noodzaak voor langdurig gebruik (met gewichtstoename na stoppen als gevolg) zijn belangrijke overwegingen