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Food intake, rates of metabolism and levels of exercise vary from person to person

The synergistic interaction between GIP and GLP-1 receptor pathways appears to create therapeutic effects that exceed what would be predicted from combining single-pathway therapies

[DOI] [PubMed] [Google Scholar] 13.Nathan D

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2012;18(7):BR286-91

Researched For Sema serves as a high-affinity, long-acting research tool for studying GLP-1 receptor activation kinetics, downstream signaling (cAMP, PKA, EPAC2), and receptor internalization/trafficking in pancreatic cell lines and heterologous expression systems