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Moreover, the acidification of the tumor microenvironment due to the secretion of lactate, the final glycolytic product, contributes to cancer cell invasiveness and immune suppression

Lancet 2009;374:160616

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It is intended for use in adults with a BMI of 30 or higher or a BMI of 27 or higher with weight-related medical conditions

In one widely reported case, a State Farm adjuster allegedly treated a victims weight as a pre-existing condition when valuing her claim

, Zhang, B
