how to keep the weight off after tirzepatide loss maintenance discontinuing GLP-1 : r/Zepbound Can Tirzepatide Help You Lose

Get safe, personalised advice to keep your treatment on track

About 70% of participants lost at least 5% of their initial body weight after taking the highest dose of Qsymia for 12 months

Some clinicians prefer to reduce the dose stepwise (for example, moving from a higher to lower maintenance dose before stopping completely) to allow for metabolic adjustment and medication changes

Avoid overreacting to a single low reading or a single morning where the scale is down

Changes reflect the placebo-subtracted effect

Poor sleep increases cortisol, drives insulin resistance, increases hunger hormones (even partially overriding GLP-1 appetite suppression), and impairs recovery from exercise