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Pancreatitis: Severe, persistent upper abdominal pain particularly pain radiating to the back may indicate acute pancreatitis, a serious adverse event associated with the incretin drug class

This may be of benefit for anyone with MCAS, and clinical trials are looking at the effectiveness of different doses.[ref][ref] Dementia prevention: Studies using data from diabetes patients showed a significant decrease in dementia for those on GLP-1s vs other diabetes medications

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The fourth embodiment of the present invention provides an improved process for the preparation of compound of formula-2 (Boc-His(PG)-Aib-OH), comprising