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There is, however, evidence to support considering closer follow-up when initiating a GLP-1 RA, particularly if rapid improvement in glycemic control is anticipated, following a baseline dilated fundus examination performed around the time of therapy initiation

102 However, it should be noted that publications demonstrating the cardiovascular benefits of GLP-1 or its analogs have utilized supraphysiological dosages

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In this state, the peptide can survive months or even years at controlled temperatures without degrading

The impact, however, extends far beyond one company, to the sprawling global weight-loss business, which pharma executives and scientists have long considered a potential gold mine

Those who live with type 2 diabetes have an increased risk of developing chronic kidney disease and are more likely to experience a major cardiovascular event in their lifetime, such as stroke, heart attack, or death