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The term triplet * refer to a high glucose (25 mM) level with 10 mM L-glutamine and 5 mM sodium butyrate

GLP-1/GLP-1R functions in different knee joint tissues OA is a whole-joint degenerative disease, and pathological changes seen in OA include degradation of cartilage, synovial inflammation and thickening of subchondral bone with osteophyte formation, associated with symptoms such as pain and stiffness

Thomas C, Gioiello A, Noriega L, Strehle A, Oury J, Rizzo G, Macchiarulo A, Yamamoto H, Mataki C, Pruzanski M, Pellicciari R, Auwerx J, Schoonjans K

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