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10.1016/S0140-6736(08)60601-7 [DOI] [PubMed] 50.Task Force for Preoperative Cardiac Risk Assessment and Perioperative Cardiac Management in Non-cardiac Surgery

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Data from clinical studies In an observational study involving 20 diabetic subjects receiving background metformin therapy, exenatide treatment over 16 weeks resulted in improved flow-mediated vasodilation of the brachial artery following 5 min of forearm ischemia, as assessed by ultrasound echocardiography, compared to patients treated with glimepiride [85]

Scientists are testing depot technologies to stretch dosing intervals even further

This age threshold reflects ongoing clinical caution regarding how such medications might affect patients who have not yet completed puberty