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The paired homeodomain transcription factor Pax-2 is expressed in the endocrine pancreas and transactivates the glucagon gene promoter

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And then the biggest, I think, issue is damning piece of research that came out and the interpretation of it was a few years ago, a study came out that said, you know what

[DOI] [PubMed] [Google Scholar] 3.Kosiborod M.N., Deanfield J., Pratley R., Borlaug B.A., Butler J., Davies M.J., Emerson S.S., Kahn S.E., Kitzman D.W., Lingvay I., et al