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The study identified a higher number of patients with retained gastric contents in those undergoing EGD alone compared to no gastric contents in those undergoing combined EGD-colonoscopy ( It is unclear if the risks are lower with the combination of holding the medication and also having a bowel prep, if one of these approaches may be sufficient to reduce risks, or if even a clear liquid diet without a bowel prep could also be just as effective

This article explains what Retatrutide is, why it appears in metabolic research, how researchers describe its receptor activity, and what types of studies have been published

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Providers may recommend gradual dose adjustments or alternative strategies depending on response and long-term goals