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18,19 Given the confounding information, there is no established DR screening protocol upon GLP-1RA initiation

56 These trials demonstrate that although orforglipron is safe and efficacious more longitudinal research is warranted to provide deeper insights into their efficacy, safety and tolerability before their potential incorporation in the pharmacological arsenal against T2DM or obesity

doi: 10.1007/s00125-009-1562-x
However, the WD+allulose group, while still showing high glycogen content, was largely protected from the development of fatty liver, and also developed less hepatic hypertrophy (weight gain) compared to the WD+stevia group (Figure 3AC)

95% CI, -0.55% to -0.12%

Human data followed: a prospective, double-blind RCT in Diabetes Care found that daily administration of Lactobacillus reuteri SD5865 increased glucose-stimulated GLP-1 release by 76% compared to placebo, with corresponding increases in insulin secretion
