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If present, discontinuation should be considered, following the ASA guidance: withholding on the day of surgery for daily formulations and 1 week prior for weekly ones

This analysis also indicated fewer acute kidney injuries with the use of SGLT2 inhibitors

The agreement includes provisions requiring certain TransCon technology-based products to be identified and advanced in metabolic diseases to maintain exclusivity in the field and additional provisions for cardiovascular diseases

These include possible exacerbation or new manifestation of tics that resolve after bupropion is withdrawn, the development of repetitive and compulsive behaviors in patients who may be vulnerable to the development of obsessive-compulsive disorder (OCD) and/or tics, and, in one case, hypomanic symptoms