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In the landmark study for semaglutide, participants were randomized to semaglutide or placebo plus lifestyle interventions

PMID 29236221

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Systematic review and meta-analysis of head-to-head trials comparing sulfonylureas and low hypoglycaemic risk antidiabetic drugs

Pair it with nutrient-dense foods like eggs, fish, leafy greens, and fruits foods already highlighted earlier in this guide

Conversely, data from clinical trials have showed an increased risk of incident heart failure with DPP4 inhibitors compared to placebo
