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Lipscombe L, Butalia S, Dasgupta K, et al
Bottom line: GLP-1 (semaglutide or tirzepatide) therapy can be highly valuable for older adults when used thoughtfully with attention to pre-existing conditions, individualized dose adjustments, and proactive risk mitigation strategies
Further examples of this chemical series have since been described (Cary et al., 2019
The mechanism of GLP-1-induced nausea involves central GLP-1R activation in the brainstem, specifically in the area postrema, which is the chemoreceptor trigger zone for vomiting
Ozempic is the brand-name medication for the active ingredient semaglutide, which primarily acts at the GLP-1 receptor alone
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