dual agonist glp-1 glucagon The Effects of GLP-1/GIP Receptor Agonism on Secretion—A Review The dual agonist action of
Description
In practical terms, intact skin blocks these molecules before they can reach circulation
However, if you are high risk for heart disease, have had a heart event or the equivalent (stroke, stent), or do not require 15-20% weight loss, semaglutide / Wegovy may be a better choice

GLP-1 also lowers glucagon secretion from pancreatic alpha cells, leading to reduced hepatic glucose production

Most experimental patches use microarray technologythousands of tiny needles that penetrate the outer skin layerbut this still requires regular replacement and carries infection risks similar to injections
Taylor R, Al-Mrabeh A, Zhyzhneuskaya S, Peters C, Barnes AC, Aribisala BS, et al
Type 2 diabetes in adults: management
