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Description
Overall, the results of the PIONEER-3 study together with other recent studies suggest that the introduction of semaglutide , the first oral compound of GLP-1RA in which the subcutaneous agent has shown a positive cardiovascular benefit, is an important addition to the growing list of pharmacological options for the treatment of type-2 diabetes
Meanwhile, other neurons only experienced temporary increases, possibly because they internalized or degraded their GLP-1 receptors, the authors explained

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