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Once youve hit your target weight, the goal is to decrease the amount of medication you need, while maintaining weight loss and a reduced appetite

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Whilst LOCF was the most commonly used method to address missing data across the trials included in the NMA, LOCF-based statistical approaches are no longer recommended due to concerns regarding the plausibility of the assumptions (ie, body weight would be unaffected by discontinuations for trial participants lost to follow-up) and the potential for bias

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If more than 3 days have passed, or if your next scheduled injection is fewer than 2 days away, skip the missed dose and continue with your regular weekly or bi-weekly schedule on the next planned date

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