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A Nature study of 27,885 people identified gene variants that predict GLP-1 weight loss and nausea risk, including one specific to Mounjaro users.

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Common versions include tirzapetide (Mounjaro/Zepbound), semaglutide (Ozempic/Wegovy/Rybelsus) and are available orally or subcutaneously (injections)

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Recent Findings Intentional weight loss via semaglutide among persons with heart failure and preserved ejection fraction and obesity significantly improves weight loss and health status as assessed by the KCCQ-CSS score and is associated with improvements in 6-min walk test

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