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Bariatric surgery was associated with greater weight loss, but GLP-1 RA therapy was associated with better outcomes

: Wegovy an adjunct to diet and exercise to reduce body weight an maintain weight reduction to reduce the risk of major adverse cardiovascular events (cardiovascular death, non-fatal myocardial infarction, or non-fatal stroke) in adults with established cardiovascular disease and either obesity or overweight

Some patients jump from 0.25 mg to 1.0 mg after just two weeks because they did not feel anything at the starting dose

A modest but significant LBM loss (2%) also occurred

However, up to 89% of participants taking efinopegdutide experienced gastrointestinal adverse events (mostly nausea, vomiting and diarrhoea) relative to 28% taking placebo and 60% taking liraglutide (86)

You are in menopause and the next day you are postmenopausal