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Background: The Rise and Regulation of Compounded GLP-1 Drugs To appreciate the significance of the FDAs latest action, some context is necessary

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Acute kidney injury occurred in 0.5% of Zepbound-treated users versus 0.2% on placebo per the FDA prescribing information, and was generally tied to dehydration from severe vomiting or diarrhea not the drug itself

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Lancet 2021;398:18111824
