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Evaluation of Out-of-Pocket costs and treatment intensification with an SGLT2 inhibitor or GLP-1 RA in patients with type 2 diabetes and cardiovascular disease

Cost Concerns The high cost of GLP-1 drugs, especially for weight loss purposes, is another driving factor behind the microdosing trend

Harder stools Increased bloating More abdominal discomfort Feeling overly full after eating Less frequent bowel motions Some people do perfectly well on GLP-1s with the right support, but others find constipation becomes significantly worse especially if hydration, food intake or fibre balance arent carefully managed

Budget for at least 6 months of treatment, ideally 12 months

Compared to adults, relatively few studies have investigated the use of GLP-1RA in pediatric patients with diabetes and obesity

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