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Switching Between Them: From Mounjaro to Semaglutide: Take last Mounjaro dose Wait one week Start semaglutide at 0.5-1.0 mg (provider determines dose) Adjust based on response From Semaglutide to Tirzepatide: Take last semaglutide dose Wait one week Start tirzepatide at 2.5-5 mg (provider determines dose) Escalate according to standard protocol Switching is safe and common

Hao Xu, [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Jayaram H, Kolko M, Friedman DS, Gazzard G

[DOI] [PubMed] [Google Scholar] 10.Feldman WB, Bloomfield D, Beall RF, Kesselheim AS

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The FDA has issued warnings which have also been contested