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Some of the key gene include: HLA-DQA1, HLA-DQB1, HLA-DRB1, INS, PTPN22, CTLA4, IL2RA, IFIH1 This autoimmune reaction is central to the development of Type 1 diabetes

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Importantly, lean MASLD patients can progress to fibrosis and cirrhosis at rates similar to their overweight counterparts, underscoring the need for early identification and intervention

Overall, GLP-1 therapies may offer a useful option for certain patients with PCOS, especially when metabolic dysfunction is a central feature