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PMCID: PMC9349974

Systemic signs severe nausea, vomiting that prevents eating, or a resting heart rate above 100 bpm are listed in the Mounjaro FDA prescribing information

and that any discrepancies from the study as originally planned (and, if relevant, registered) have been explained

Compounded GLP-1/GIP treatments including tirzepatide start at $149 per month on the yearly plan with the microdosing option, and $179 per month on the standard compounded plan

in humans, this occurs even before changes in body weight 145,146

Expert consensus suggests that patients taking GLP-1 receptor agonists or dual GIP/GLP-1 receptor agonists may benefit from 1.01.5 grams of protein per kilogram of ideal or adjusted body weight daily to support lean muscle mass preservation