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While these emerging medications hold promise for advancements in obesity-related healthcare, there is limited knowledge to date on the effectiveness of these drugs among diverse populations, and to what extent these treatments are accessible to groups disproportionately affected by obesity

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By using nationwide data and an innovative methodological approach, our team was able to expand the findings of previous trials to larger populations more representative of HFpEF patients treated in clinical practice, Krger said

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Inhibiting GABA A receptors in the paraventricular nucleus of the hypothalamus (PVN), the control centre of the SNS, abolishes the enhancing effect on insulin secretion induced by OB GLP-1R